Analysis of materials | Pharmaceutical analyses

Polyolefins are obtained by polymerisation of ethylene or propylene or by copolymerisation of these substances with not more than 25 per cent of higher homologues (C4 to C10) or of carboxylic acids or of esters. Certain materials may be mixtures of polyolefins.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Polyethylene without additives is obtained by polymerisation of ethylene under high pressure in the presence of oxygen or free-radical-forming initiators as catalyst.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

 Polyethylene with additives is obtained by polymerisation of ethylene under pressure in the presence of a catalyst or by copolymerisation of ethylene with not more than 25 per cent of higher alkene homologues (C3 to C10).

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Polypropylene consists of the homopolymer of propylene or of a copolymer of propylene with not more than 25 per cent of ethylene or of a mixture (alloy) of polypropylene with not more than 25 per cent of polyethylene. It may contain additives.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Poly(ethylene - vinyl acetate), complying with the following requirements, is suitable for the manufacture of containers and tubing for total parenteral nutrition preparations. It is obtained by copolymerisation of mixtures of ethylene and vinyl acetate.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Silicone oil used as a lubricant is a poly(dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. Different grades exist which are characterised by a number indicating the nominal viscosity placed after the name.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

ilicone elastomer complying with the following requirements is suitable for the manufacture of closures and tubing. Silicone elastomer is obtained by cross-linking a linear polysiloxane constructed mainly of dimethylsiloxy units with small quantities of methylvinylsiloxy groups; the chain ends are blocked by trimethylsiloxy or dimethylvinylsiloxy groups.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Materials based on non-plasticised poly(vinyl chloride) that comply with the following specifications are suitable for the manufacture of containers for non-injectable aqueous solutions. They may also be used for solid forms for oral administration and in some cases, subject to special studies on the compatibility of the container with its contents, these materials may be suitable for the preparation of containers for suppositories. They consist of 1 or more poly(vinyl chloride/vinyl acetate) or of a mixture of poly(vinyl chloride) and poly(vinyl acetate) or of poly(vinyl chloride).

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Materials based on non-plasticised poly(vinyl chloride) for containers for solid dosage forms for oral administration are suitable for the manufacture of sheets or containers, and consist of 1 or more poly(vinyl chloride/vinyl acetate) or of a mixture of poly(vinyl chloride) and poly(vinyl acetate) or of poly(vinyl chloride).

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Materials based on plasticised poly(vinyl chloride) contain not less than 55 per cent of poly(vinyl chloride) and contain various additives, in addition to the high-molecular-mass polymer obtained by polymerisation of vinyl chloride.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS

Polyethylene terephthalate is obtained from the polymerisation of terephthalic acid or dimethyl terephthalate with ethylene glycol. Isophthalic acid, dimethyl isophthalate, 1,4-bis(hydroxymethyl)cyclohexane (cyclohexane-1,4-dimethanol) or diethylene glycol may be used in the polymerisation. It may contain not more than 0.5 per cent of silica or silicates and colouring matter approved by the competent authority.

Our laboratory equipment for this method: ATR-FT/IR, GC-MS 1, UV-VIS